Optimisation and usefulness of quantitative analysis of 18F-florbetapir PET

Abstract

We have derived and validated mcSUVR thresholds for Aβ+/Aβ- ¹⁸F-florbetapir studies. This work demonstrates that division into sub types improves reader accuracy and agreement and quantification accuracy in scans with typical presentation and highlights the atypical presentations not suited to global SUVR quantification.