Induction of Apoptosis and Inhibition of Invasion in Gastric Cancer Cells by Titanium Dioxide Nanoparticles

Abstract

Various forms of TiO₂ nanoparticles reduced cell proliferation and induced apoptosis in cancer cells. Some forms of TiO₂ nanoparticles such as brookite BSA also inhibited cell invasion. PEG-amorph TiO₂ nanoparticles increased cell invasion. These differences seem to be due to the effects of different configurations of TiO₂ nanoparticles. TiO₂ may provide a new strategy for cancer treatment and more studies are needed.