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Stemona alkaloids suppress the positive feedback loop between M2 polarization and fibroblast differentiation by inhibiting JAK2/STAT3 pathway in fibroblasts and CXCR4/PI3K/AKT1 pathway in macrophages

InflammationCytokineSignal TransductionM2 PolarizationTumor MicroenvironmentSignaling PathwayReceptor Tyrosine KinaseAutophagyImmunologyStemona AlkaloidsPhagocyteMedicineCell BiologyCell SignalingCellular PhysiologyPositive Feedback Loop