Concepedia

Pharmacokinetic properties of enantiomerically pure GluN2B selective NMDA receptor antagonists with 3-benzazepine scaffold

Frederik Börgel, F Galla, Kirstin Lehmkuhl, Dirk Schepmann, Simon M. Ametamey, Bernhard Wünsch

Journal of Pharmaceutical and Biomedical Analysis · 2019 · 28 citations · 31 references

DOI

Concepts

References

31

Crystal structure of a heterotetrameric NMDA receptor ion channel

Erkan Karakaş, Hiro Furukawa · Science · 2014 · 601 citations

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NMDA receptor structures reveal subunit arrangement and pore architecture

Chia-Hsueh Lee, Wei Lü, Jennifer Carlisle Michel et al. · Nature · 2014 · 522 citations · Full text

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When poor solubility becomes an issue: From early stage to proof of concept

Sven Stegemann, F. Leveiller, D. Franchi et al. · European Journal of Pharmaceutical Sciences · 2007 · 504 citations

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When poor solubility becomes an issue: from early stage to proof of concept

Sven Stegemann · 2007 · 390 citations

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The importance of plasma protein binding in drug discovery

George L. Trainor · Expert Opinion on Drug Discovery · 2007 · 344 citations

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