QTL analysis reveals genomic variants linked to high-temperature fermentation performance in the industrial yeast

Abstract

This work revealed eight novel causative genes and SNP variants closely associated with high-temperature fermentation performance. Among these genes, <i>VPS34</i> and <i>DAP1</i> would be good targets for improving high-temperature fermentation of the industrial yeast. It also showed that loss of heterozygosity of causative genes could contribute to the improvement of high-temperature fermentation capacities. Our findings would provide guides to develop more robust and thermotolerant strains for the industrial production of ethanol.