Studying the effect of 0.14 THz radiation on human dermal fibroblasts

Abstract

The effects of coherent monochromatic 0.14 THz radiation on human dermal fibroblasts were experimentally investigated using a solid-state radiation source based on an IMPATT diode. The fibroblast cells were exposed for 20 minutes to a wave beam of different power (10, 30, 50, 70, and 100 mW) and such parameters as proliferative activity, wound closure percentage, and the level of nitric oxide production in irradiated cells were studied. No tangible changes in the examined parameters were revealed, thereby allowing us to conclude that the low-frequency THz radiation does not affect the functional activity of the human dermal fibroblasts.