Immobilization of amidase into a magnetic hierarchically porous metal–organic framework for efficient biocatalysis

Abstract

A novel magnetic hierarchically porous metal-organic framework (MOF) has been successfully fabricated via a modulator-induced defect-formation strategy. Amidase for the first time has been immobilized into this magnetic carrier and the resultant bio-composite exhibits superior enzymatic catalysis performance compared to the free enzyme and its counterparts without hierarchical porosity.