Synthesis of Aza‐Heteroaromatic Dithiocarbamates via Cross‐Coupling Reactions of Aza‐Heteroaromatic Bromides with Tetraalkylthiuram Disulfides

Abstract

The preparation of various aza‐heteroaromatic dithiocarbamates from aza‐heteroaromatic bromides and tetraalkylthiuram disulfides is reported. The transformation provides a convenient procedure, with good yields and functional group tolerance to various important nitrogen‐containing heteroaromatic dithiocarbamates such as benzothiazole, quinoline, pyridine, and pyrazine motifs. This protocol allows the facile synthesis of some potential biologically active compounds.