Cucurbitacins extracted from Cucumis melo L. (CuEC) exert a hypotensive effect via regulating vascular tone

Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway

Yujuan Dong, Bojing Lu, Xiongwen Zhang et al. · Carcinogenesis · 2010 · 182 citations · Full text

Medicine, Oncology, Pharmacology +15

Cucurbitacin D exhibits potent anti-cancer activity in cervical cancer

Mohammed Sikander, Bilal Bin Hafeez, Shabnam Malik et al. · Scientific Reports · 2016 · 82 citations · Full text

Medicine, Oncology, Pharmacology +17

Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/β-catenin signaling axis

Samriddhi Shukla, Sonam Sinha, Sajid Khan et al. · Scientific Reports · 2016 · 80 citations · Full text

Medicine, Oncology, Pharmacology +17

Cucurbitacin B, a novel <i>in vivo</i> potentiator of gemcitabine with low toxicity in the treatment of pancreatic cancer

Gabriela B. Iwanski, Dhong H Lee, Shlomit En‐Gal et al. · British Journal of Pharmacology · 2010 · 77 citations · Full text

Medicine, Oncology, Pharmacology +16

Cucurbitacin B Induces Hypoglycemic Effect in Diabetic Mice by Regulation of AMP-Activated Protein Kinase Alpha and Glucagon-Like Peptide-1 via Bitter Taste Receptor Signaling

Kang‐Hoon Kim, In‐Seung Lee, Ji Young Park et al. · Frontiers in Pharmacology · 2018 · 67 citations · Full text

Life Sciences, Endocrinology, Pharmacology +17