Concepedia

Co(II)-Catalyzed Regioselective Pyridine C–H Coupling with Diazoacetates

Haisheng Xie, Youxiang Shao, Jiao Gui, Jianyong Lan, Zhipeng Liu, Zhuofeng Ke, Yuanfu Deng, Huanfeng Jiang, Wei Zeng

Organic Letters · 2019 · 23 citations · 34 references

DOI

Abstract

A Co(II)-catalyzed pyridyl C-H bond carbenoid insertion with α-diazoacetates has been realized. This transformation features a highly regioselective C-C bond formation at the C3-position of pyridines, providing an efficient access to diverse α-aryl-α-pyridylacetates.

References

34

Palladium-Catalyzed C−H Functionalization of Pyridine <i>N</i>-Oxides: Highly Selective Alkenylation and Direct Arylation with Unactivated Arenes

Seung Hwan Cho, Seung Jun Hwang, Sukbok Chang · Journal of the American Chemical Society · 2008 · 668 citations

A Coupling of Benzamides and Donor/Acceptor Diazo Compounds To Form γ-Lactams via Rh(III)-Catalyzed C–H Activation

Todd K. Hyster, Kyle E. Ruhl, Tomislav Rovis · Journal of the American Chemical Society · 2013 · 488 citations

Rh-Catalyzed Intermolecular Carbenoid Functionalization of Aromatic C–H Bonds by α-Diazomalonates

Wai-Wing Chan, Siu-Fung Lo, Zhongyuan Zhou et al. · Journal of the American Chemical Society · 2012 · 475 citations

Rh(III)-Catalyzed Synthesis of Multisubstituted Isoquinoline and Pyridine <i>N</i>-Oxides from Oximes and Diazo Compounds

Zhuangzhi Shi, Dennis C. Koester, Melissa Boultadakis‐Arapinis et al. · Journal of the American Chemical Society · 2013 · 445 citations

, , +12

Highly Site-Selective Direct C–H Bond Functionalization of Phenols with α-Aryl-α-diazoacetates and Diazooxindoles via Gold Catalysis

Zhunzhun Yu, Ben Ma, Mingjin Chen et al. · Journal of the American Chemical Society · 2014 · 438 citations

, , +11