Progressive increase of FcεRI expression across several PBMC subsets is associated with atopy and atopic asthma within school‐aged children

Abstract

Our data suggest that the expression pattern of FcεRI on DC and basophils differentiates asthmatic from non-asthmatic atopic children. Given the significant immune modulatory effects observed as a consequence of FcεRI expression, this altered expression pattern is likely to contribute to asthma pathology in children.