The role of ArlRS in regulating oxacillin susceptibility in methicillin-resistant <i>Staphylococcus aureus</i> indicates it is a potential target for antimicrobial resistance breakers

Jinna Bai, Xiaoyi Zhu, Ke‐Qing Zhao, Ying-jie Yan, Tao Xu, Jiaxue Wang, Jinxing Zheng, Wei Huang, Le Shi, Yongpeng Shang,

Emerging Microbes & Infections · 2019 · 40 citations · 51 references

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Abstract

= 5.47 μM). Oritavancin had synergy effect on oxacillin activity against the MRSA strains in both planktonic and biofilm state. Our data suggest that ArlRS is an attractive target for breaking antimicrobial resistance of MRSA.

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