The regulation of melanocyte-stimulating hormone on the pigment granule dispersion in the xanthophores and melanophores of the large yellow croaker (Larimichthys crocea)

Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice

Dennis Huszar, Catherine Lynch, Victoria Fairchild-Huntress et al. · Cell · 1997 · 3K citations · Full text

Medicine, Endocrinology, Neuroscience +11

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome

Wei Fan, Bruce A. Boston, Robert A. Kesterson et al. · Nature · 1997 · 1.9K citations

Life Sciences, Neurobiology, Neuroscience +14

Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain.

Kathleen G. Mountjoy, Marty Mortrud, Malcolm J. Low et al. · Molecular Endocrinology · 1994 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

A Novel Role for Mc1r in the Parallel Evolution of Depigmentation in Independent Populations of the Cavefish Astyanax mexicanus

Joshua B. Gross, Richard Borowsky, Clifford J. Tabin · PLoS Genetics · 2009 · 307 citations · Full text

Life Sciences, Biology, Genetics +15

Melanocortin 4 receptor mutations contribute to the adaptation of cavefish to nutrient-poor conditions

Ariel C. Aspiras, Nicolas Rohner, Brian Martineau et al. · Proceedings of the National Academy of Sciences · 2015 · 279 citations · Full text

Life Sciences, Evolutionary Biology, Genetics +17