Impact of <scp>SBRT</scp> fractionation in hypoxia dose painting — Accounting for heterogeneous and dynamic tumor oxygenation

Abstract

The method to account for heterogeneous and dynamic hypoxia in target volume segmentation and dose prescription based on ¹⁸ F-HX4-PET imaging appears feasible in NSCLC patients. The distribution of oxygen partial pressure within HTV could impact the required prescribed dose more than the size of the volume.