Publication | Open Access
Posterior reversible encephalopathy syndrome induced by nivolumab immunotherapy for non–small‐cell lung cancer
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Citations
16
References
2019
Year
HypertensionNon–small‐cell Lung CancerNeurological SyndromeNeurological DisorderImmunologyBrain LesionImmunotherapyCerebral Vascular RegulationNeurovascular DiseaseNeuro-oncologyOncologyTumor ImmunityIntracranial PressureBrain InjuryNeurologyNeuropathologyRadiation OncologyHealth SciencesOphthalmologyMedicineSevere HypertensionCerebral Blood FlowNivolumab ImmunotherapyLung CancerEndothelial DysfunctionBronchial NeoplasmImmune Checkpoint InhibitorNeuroscienceCentral Nervous SystemStroke
Posterior reversible encephalopathy syndrome (PRES) is a neurological syndrome characterized by vasogenic cerebral edema with predominantly posterior involvement. Uncontrolled severe hypertension and endothelial dysfunction have been implicated as two main mechanisms. Clinicians should notice the development of PRES in hypertensive patients accompanying neurological changes, such as impaired vision and consciousness.
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