Concepedia

Downregulation of A2AR by siRNA loaded PEG-chitosan-lactate nanoparticles restores the T cell mediated anti-tumor responses through blockage of PKA/CREB signaling pathway

Ali Masjedi, Hadi Hassannia, Fatemeh Atyabi, Ali Rastegari, Mohammad Hojjat‐Farsangi, Afshin Namdar, Hassan Soleimanpour, Gholamreza Azizi, Afshin Nikkhoo, Ghasem Ghalamfarsa,

International Journal of Biological Macromolecules · 2019 · 80 citations · 26 references

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26

A2A adenosine receptor protects tumors from antitumor T cells

Akio Ohta, Elieser Gorelik, Simon J. Prasad et al. · Proceedings of the National Academy of Sciences · 2006 · 1K citations

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Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis

John Stagg, Upulie Divisekera, Nicole M. McLaughlin et al. · Proceedings of the National Academy of Sciences · 2010 · 567 citations · Full text

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A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells

Paul E. Zarek, Ching-Tai Huang, Eric R. Lutz et al. · Blood · 2007 · 498 citations · Full text

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Targeting CD73 Enhances the Antitumor Activity of Anti-PD-1 and Anti-CTLA-4 mAbs

Bertrand Allard, Sandra Pommey, Mark J. Smyth et al. · Clinical Cancer Research · 2013 · 451 citations

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The development and immunosuppressive functions of CD4+ CD25+ FoxP3+ regulatory T cells are under influence of the adenosine-A2A adenosine receptor pathway

Akio Ohta, Manasa Madasu, Michail V. Sitkovsky · Frontiers in Immunology · 2012 · 391 citations · Full text

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