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Downregulation of A2AR by siRNA loaded PEG-chitosan-lactate nanoparticles restores the T cell mediated anti-tumor responses through blockage of PKA/CREB signaling pathway

Peg-chitosan-lactate NanoparticlesNanomedicineNovel TherapyAnti-tumor ResponsesImmunologyTumor TargetingAnti-cancer AgentT CellImmunotherapyMedicineCell BiologyTumor MicroenvironmentTumor Biology