Advances in optogenetic regulation of gene expression in mammalian cells using cryptochrome 2 (CRY2)

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

Manfred Gossen, Heidelberg Bujard · Proceedings of the National Academy of Sciences · 1992 · 5K citations

Life Sciences, Genetics, Molecular Biology +17

Transcriptional Activation by Tetracyclines in Mammalian Cells

Manfred Gossen, Sabine Freundlieb, Gabriele Bender et al. · Science · 1995 · 2.5K citations

Life Sciences, Molecular Biology, Molecular Genetics +17

Cre recombinase: The universal reagent for genome tailoring

András Nagy · genesis · 2000 · 1.2K citations

Life Sciences, Genetics, Molecular Biology +16

Rapid blue-light–mediated induction of protein interactions in living cells

Matthew J. Kennedy, Robert M. Hughes, Leslie A Peteya et al. · Nature Methods · 2010 · 1.2K citations

Natural Sciences, Biophysics, Cell Biology +11

Regulation of Cre Recombinase Activity by Mutated Estrogen Receptor Ligand-Binding Domains

Robert Feil, J D Wagner, Daniel METZGER et al. · Biochemical and Biophysical Research Communications · 1997 · 1K citations

Life Sciences, Genetics, Molecular Biology +14