Angiopoietin 1 influences ischemic reperfusion renal injury via modulating endothelium survival and regeneration

Abstract

Altogether, the augmentation and downregulation of angiopoietin 1 attenuated renal damage and impaired renal recovery, respectively, by influencing the survival/regeneration of the endothelium. The manipulation of angiopoietin 1 represents a novel therapeutic approach for the treatment of ischemic kidney injury.