Concepedia

Predicting drug-target interaction network using deep learning model

Jiaying You, R.D. McLeod, Pingzhao Hu

Computational Biology and Chemistry · 2019 · 150 citations · 33 references

Concepts

Life SciencesBioinformaticsPharmacologyDrug DiscoveryMolecular PharmacologySystems PharmacologyBinding Affinity PredictionDrug Target InformaticsDrug-target Interaction MappingDrug-target Interaction NetworksMolecular Interaction NetworksNetwork PharmacologyCompound-target Interaction PredictionDrug-target Graph EmbeddingDrug-target Interaction AnalysisDrug-target Network ConstructionNetwork-based Drug-target Prediction

References

33

Adam: A Method for Stochastic Optimization

Diederik P. Kingma, Jimmy Ba · UvA-DARE (University of Amsterdam) · 2014 · 84.8K citations · Full text

Computing, Computer Science, Algorithms +16

Dropout: a simple way to prevent neural networks from overfitting

Nitish Srivastava, Geoffrey E. Hinton, Alex Krizhevsky et al. · 2014 · 34.3K citations

Computing, Computer Science, Artificial Intelligence +12

Regularization Paths for Generalized Linear Models via Coordinate Descent

Jerome H. Friedman, Trevor Hastie, Robert Tibshirani · Journal of Statistical Software · 2010 · 17.1K citations · Full text

Natural Sciences, Computer Science, Mathematics +17

Regularization Paths for Generalized Linear Models via Coordinate Descent.

Jerome H. Friedman, Trevor Hastie, Rob Tibshirani · PubMed · 2010 · 14K citations · Full text

Natural Sciences, Computer Science, Mathematics +17

Database resources of the National Center for Biotechnology Information: update

David Wheeler · Nucleic Acids Research · 2003 · 11K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17