Journal of Biomedical Nanotechnology · 2019 · 14 citations · 0 references
PharmacyPharmaceuticsPharmacologyDrug DeliveryDrug DesignNanoparticle Drug DeliveryAntiretroviral TherapyAntiviral TherapyNanocarriers For TherapeuticsNanomedicineNanoparticle DesignPeptide DeliveryCellular Uptake EfficiencyHiv Antiretroviral TherapyHuman Immunodeficiency Virus LatencyLatency Reversal TherapyLatent ReservoirsPeptide NanoparticlesPeptide Self-assemblySelf-assembling Nanoparticles
. Increased cellular drug uptake made the PNP-P more effective than panobinostat alone. Therefore, this strategy demonstrates that nanotechnology can help improve the activation of latent HIV, and this study lays a foundation for further development of LRA delivery systems for use against an HIV reservoir.