Stereoselective Synthesis of Vinylboronates by Rh‐Catalyzed Borylation of Stereoisomeric Mixtures

Abstract

Summary of main observation and conclusion The stereoselective preparation of vinylboronates via rhodium‐catalyzed borylation of E / Z mixtures of vinyl actetates is described, and this method was also extended to synthesis of vinyldiboronates. These transformations feature high functional group compatibility and mild reaction conditions. Control experiments support a mechanism that involved a Rh‐catalyzed borylation‐isomerization sequence. The isomerization of ( Z )‐vinylboronates to ( E )‐isomers was also demonstrated.