Mutations in <i>NLRP2</i> and <i>NLRP5</i> cause female infertility characterised by early embryonic arrest

Abstract

<i>NLRP2</i> and <i>NLRP5</i> are novel mutant genes responsible for human early embryonic arrest. This finding provides additional potential diagnostic markers for patients with recurrent failure of ART and helps us to better understand the genetic basis of female infertility characterised by early embryonic arrest.