Xenon-129 MRI detects ventilation deficits in paediatric stem cell transplant patients unable to perform spirometry

Abstract

Lung ventilation deficits were detected using hyperpolarised ¹²⁹Xe gas MRI in asymptomatic paediatric HSCT patients and in a subgroup who were unable to perform reliable spirometry. ¹²⁹Xe MRI provides a reliable imaging-based assessment of pulmonary involvement in this potentially difficult to diagnose paediatric population.