Histologic Characterization of Polymethylmethacrylate Dermal Filler Biostimulatory Properties in Human Skin

Abstract

Polymethylmethacrylate-collagen gel filler stimulates collagen-3 and procollagen-1 when injected into human skin. This combination of neocollagenesis followed by microencapsulation of PMMA microspheres in the new tissue provides for long-lasting results.