Rho‐kinase inhibitor Y‐27632 downregulates LPS‐induced IL‐6 and IL‐8 production via blocking p38 MAPK and NF‐κB pathways in human gingival fibroblasts

Abstract

Rho-kinase inhibitor Y-27632 downregulates LPS-induced IL-6 and IL-8 production by blocking NF-κB and p38 MAPK activation in HGFs.