GABRP regulates chemokine signalling, macrophage recruitment and tumour progression in pancreatic cancer through tuning KCNN4-mediated Ca <sup>2+</sup> signalling in a GABA-independent manner - Concepedia

Concepedia

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GABRP regulates chemokine signalling, macrophage recruitment and tumour progression in pancreatic cancer through tuning KCNN4-mediated Ca <sup>2+</sup> signalling in a GABA-independent manner

192

Citations

33

References

2019

Year

Shu-Heng Jiang, Lili Zhu, Man Zhang, Rongkun Li, Qin Yang, Jiangyu Yan, Ce Zhang, Jian‐Yu Yang, Fangyuan Dong, Miao Dai,

Abstract

Overexpressed GABRP exhibits an immunomodulatory role in PDAC in a neurotransmitter-independent manner. Targeting GABRP or its interaction partner KCNN4 may be an effective therapeutic strategy for PDAC.

References

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