Concepedia

Phase 2, Randomized, Dose-finding Studies of Omidenepag Isopropyl, a Selective EP2 Agonist, in Patients With Primary Open-angle Glaucoma or Ocular Hypertension

Makoto Aihara, Fenghe Lu, Hisashi Kawata, Akihiro Iwata, Kathy Liu, Noriko Odani‐Kawabata, Naveed Shams

Journal of Glaucoma · 2019 · 50 citations · 17 references

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Abstract

Omidenepag isopropyl demonstrated stable IOP-lowering effects and was well tolerated; 0.002% was identified as the optimal dose for phase 3 investigation.

References

17

The number of people with glaucoma worldwide in 2010 and 2020

Harry A. Quigley · British Journal of Ophthalmology · 2006 · 7.3K citations · Full text

Primary Open-Angle Glaucoma Preferred Practice Pattern® Guidelines

Bruce E. Prum, Lisa F. Rosenberg, Steven J. Gedde et al. · Ophthalmology · 2015 · 592 citations

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Ocular Surface Disease and Quality of Life in Patients With Glaucoma

Simon E. Skalicky, Ivan Goldberg, Peter McCluskey · American Journal of Ophthalmology · 2011 · 244 citations

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Diurnal Variation of Corneal and Corneal Epithelial Thickness Measured Using Optical Coherence Tomography

Yunwei Feng, Jalazah Varikooty, Trefford Simpson · Cornea · 2001 · 181 citations

A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure

Hélène Choquet, Khanh K. Thai, Jie Yin et al. · Nature Communications · 2017 · 113 citations · Full text