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Pyrazoles containing thiophene, thienopyrimidine and thienotriazolopyrimidine as COX-2 selective inhibitors: Design, synthesis, in vivo anti-inflammatory activity, docking and in silico chemo-informatic studies

Vivo Anti-inflammatory ActivityMedicinal ChemistryMedicineDrug DiscoverySilico Chemo-informatic StudiesRational Drug DesignPharmacological AgentCox-2 Selective InhibitorsPharmacotherapyAnti-cancer AgentDrug DevelopmentPharmacologyBiomolecular Engineering