<i>Staphylococcus aureus</i> infected embolic stroke upregulates Orm1 and Cxcl2 in a rat model of septic stroke pathology

Abstract

Septic embolic stroke caused brain abscesses, increased mortality and upregulated Orm1 and Cxcl2 gene expressions compared to non-infected embolic stroke. The dramatic Orm1 increase observed in the septic group is unprecedented and suggests a significant biological role of Orm1 during septic neuroinflammation.