Overexpression of CCN1 in Het1A cells attenuates bile-induced esophageal metaplasia through suppressing non-canonical NFκB activation

The Distinct Roles of TRAF2 and RIP in IKK Activation by TNF-R1

Anne Devin, Amy Cook, Yong Lin et al. · Immunity · 2000 · 430 citations · Full text

Life Sciences, Immunology, Molecular Biology +12

Bile acids in combination with low pH induce oxidative stress and oxidative DNA damage: relevance to the pathogenesis of Barrett’s oesophagus

Katerina Dvorak, C. M Payne, Melissa Chavarria et al. · Gut · 2006 · 248 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

TRAF2 Differentially Regulates the Canonical and Noncanonical Pathways of NF-κB Activation in Mature B Cells

Adrian P. Grech, Michelle Amesbury, Tyani D. Chan et al. · Immunity · 2004 · 215 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Composition and concentration of bile acid reflux into the esophagus of patients with gastroesophageal reflux disease

W. K. H. Kauer, Jeffrey H. Peters, Tom R. DeMeester et al. · Surgery · 1997 · 207 citations

Medicine, Clinical Sciences, Internal Medicine +12

Short exposure of oesophageal mucosa to bile acids, both in acidic and weakly acidic conditions, can impair mucosal integrity and provoke dilated intercellular spaces

Ricard Farré, Hannah van Malenstein, Rita De Vos et al. · Gut · 2008 · 204 citations

Medicine, Pharmacology, Physiology +17