Using 2-aminobenzimidazole derivatives to inhibit <i>Mycobacterium smegmatis</i> biofilm formation

Abstract

Biofilm formation by mycobacteria can lead to enhanced antibiotic tolerance. Herein, we report on the identification of a series of 2-aminobenzimidazole (2-ABI) derivatives that potently inhibit biofilm formation by <i>Mycobacterium smegmatis</i>.