Open Forum Infectious Diseases · 2019 · 49 citations · 10 references
Veterinary MedicineInfectious DiseasesMicrobiologyAntimicrobial PharmacotherapyDiagnostic MicrobiologyMedical MicrobiologyAntibiotic ResistanceAntimicrobial TherapyBacterial InfectionsCentral Nervous System InfectionsClinical BacteriologyMeningitis Antibiotic TherapyMeningitis DiagnosisMicrobiologic Diagnosis
Abstract The impact of antibiotic therapy on the diagnosis of healthcare–associated ventriculitis and meningitis (HCAVM) is unknown. Antibiotics were administered before obtaining cerebrospinal fluid (CSF) in 217 out of 326 (66%) patients with HCAVM, and they impacted the sensitivity of the cerebrospinal fluid Gram stain and culture (P ≤ .004).
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