D-methionine alleviates cisplatin-induced mucositis by restoring the gut microbiota structure and improving intestinal inflammation

Abstract

D-methionine protects against cisplatin-induced intestinal damage through antioxidative and anti-inflammatory effects. By enhancing growth of beneficial bacteria (Lachnospiraceae and <i>Lactobacillus</i>), D-methionine attenuates gut microbiome imbalance caused by cisplatin and maintains gut homeostasis.