Concepedia

Emergence of clonal fluconazole-resistant Candida parapsilosis clinical isolates in a multicentre laboratory-based surveillance study in India

Ashutosh Singh, Pradeep Kumar Singh, Theun de Groot, Anil Kumar, Purva Mathur, Bansidhar Tarai, Neelam Sachdeva, Gargi Upadhyaya, Smita Sarma, Jacques F. Meis,

Journal of Antimicrobial Chemotherapy · 2019 · 80 citations · 42 references

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Abstract

We report a novel K143R amino acid substitution in ERG11p causing fluconazole resistance in C. parapsilosis. Fluconazole-non-susceptible C. parapsilosis isolates carrying the novel K143R amino acid substitution should be identified in clinical microbiology laboratories to prevent further clonal transmission.

References

42

Incidence of Bloodstream Infections Due to <i>Candida</i> Species and In Vitro Susceptibilities of Isolates Collected from 1998 to 2000 in a Population-Based Active Surveillance Program

Rana Hajjeh, André N. Sofair, Lee H. Harrison et al. · Journal of Clinical Microbiology · 2004 · 649 citations · Full text

Epidemiology and Predictors of Mortality in Cases of <i>Candida</i> Bloodstream Infection: Results from Population-Based Surveillance, Barcelona, Spain, from 2002 to 2003

Benito Almirante, Dolors Rodríguez-Pardo, Benjamin J. Park et al. · Journal of Clinical Microbiology · 2005 · 566 citations · Full text

, , +14

A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009–17) in India: role of the ERG11 and FKS1 genes in azole and echinocandin resistance

Anuradha Chowdhary, Anupam Prakash, Cheshta Sharma et al. · Journal of Antimicrobial Chemotherapy · 2017 · 558 citations · Full text

Multidrug-Resistant Candida auris Misidentified as Candida haemulonii: Characterization by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry and DNA Sequencing and Its Antifungal Susceptibility Profile Variability by Vitek 2, CLSI Broth Microdilution, and Etest Method

Shallu Kathuria, Pradeep Kumar Singh, Cheshta Sharma et al. · Journal of Clinical Microbiology · 2015 · 525 citations · Full text

, , +18

Epidemiology of Candidemia in Brazil: a Nationwide Sentinel Surveillance of Candidemia in Eleven Medical Centers

Arnaldo Lopes Colombo, Márcio Nucci, Benjamin J. Park et al. · Journal of Clinical Microbiology · 2006 · 521 citations · Full text