Concepedia

Role of PD-L1 Expression in Non-Small Cell Lung Cancer and Their Prognostic Significance according to Clinicopathological Factors and Diagnostic Markers

Konrad Pawełczyk, Aleksandra Piotrowska, Urszula Ciesielska, Karolina Jabłońska, Natalia Glatzel-Plucińska, Jędrzej Grzegrzółka, Marzenna Podhorska‐Okołów, Piotr Dzięgiel, Katarzyna Nowińska

International Journal of Molecular Sciences · 2019 · 197 citations · 38 references

DOIFull text

Open access

Abstract

PD-L1 expression seems to be associated with increased tumor proliferation and aggressiveness as well as shorter patient survival in NSCLC, predominantly in the AC group.

References

38

Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer

Martin Reck, Delvys Rodríguez‐Abreu, Andrew Robinson et al. · New England Journal of Medicine · 2016 · 9.8K citations · Full text

Pensar y educar

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Non–Small Cell Lung Cancer, Version 5.2017, NCCN Clinical Practice Guidelines in Oncology

David S. Ettinger, Douglas E. Wood, Dara L. Aisner et al. · Journal of the National Comprehensive Cancer Network · 2017 · 1.3K citations

PD‐1 inhibits T‐cell receptor induced phosphorylation of the ZAP70/CD3ζ signalosome and downstream signaling to PKCθ

Kelly-Ann Sheppard, Lori Fitz, Julie M. Lee et al. · FEBS Letters · 2004 · 761 citations

Programmed death ligand-1 expression in non-small cell lung cancer

Vamsidhar Velcheti, Kurt A. Schalper, Daniel Carvajal et al. · Laboratory Investigation · 2013 · 750 citations · Full text

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