Survivin facilitates T‐helper 2–biased inflammation in the airway

Abstract

Survivin facilitates the development of biased Th2 polarization through promoting expression of interleukin 4 (IL-4) and impairing the AICD machinery of CD4⁺ T cells. To modulate the expression of survivin in CD4⁺ T cells has the translational potential in the treatment of allergic diseases.