Interleukin-6 Inhibitor Suppresses Hyperalgesia Without Improvement in Osteoporosis in a Mouse Pain Model of Osteoporosis

Efficient Analysis of Experimental Observations

W. J. Dixon · The Annual Review of Pharmacology and Toxicology · 1980 · 2.2K citations

Public Health, Biostatistics, Pharmacology +7

Prevalence of knee osteoarthritis, lumbar spondylosis, and osteoporosis in Japanese men and women: the research on osteoarthritis/osteoporosis against disability study

Noriko Yoshimura, Shigeyuki Muraki, Hiroyuki Oka et al. · Journal of Bone and Mineral Metabolism · 2009 · 820 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17

Impaired skeletal development in interleukin‐6–transgenic mice: A model for the impact of chronic inflammation on the growing skeletal system

Fabrizio De Benedetti, Nadia Rucci, Andrea Del Fattore et al. · Arthritis & Rheumatism · 2006 · 321 citations

Medicine, Developmental Biology, Immunology +17

Callus mineralization and maturation are delayed during fracture healing in interleukin-6 knockout mice

Xu Yang, Benjamin F. Ricciardi, Alexia Hernandez-Soria et al. · Bone · 2007 · 305 citations · Full text

Medicine, Immunology, Bone Metabolism +12

The Functional Block of TNF but Not of IL-6 Prevents Bone Loss in Ovariectomized Mice

Robert B. Kimble, Steve Bain, Roberto Pacifici · Journal of Bone and Mineral Research · 1997 · 242 citations · Full text

Medicine, Endocrinology, Immunology +17