Concepedia

Efficacy of Intranasal Administration of the Recombinant Endolysin SAL200 in a Lethal Murine Staphylococcus aureus Pneumonia Model

Ji Yun Bae, Kang Il Jun, Chang Kyung Kang, Kyoung‐Ho Song, Pyoeng Gyun Choe, Ji Hwan Bang, Eu Suk Kim, Sang‐Won Park, Hong Bin Kim, Nam Joong Kim,

Antimicrobial Agents and Chemotherapy · 2019 · 46 citations · 15 references

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Concepts

Abstract

SAL200 is derived from a phage endolysin and is a novel candidate drug for the treatment of Staphylococcus aureus infection. We investigated the efficacy of the recombinant endolysin SAL200 in a lethal murine pneumonia model.

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