Cubo · 2018 · 40 citations · 15 references
Veterinary MedicineInfectious Disease ControlInfectious DiseasesCommunicable Disease ControlImmunizationInfectious Disease EpidemiologyInfectious Disease DynamicsInfectious Disease PreventionOutbreak ControlTransmission DynamicsVaccinationControlsEpidemic ModelsEpidemic Models With DelayEpidemic SpreadingIncidence Function ModelingInfectious Disease ModelsMathematical Modeling Of EpidemicsTreatment Strategies
In this paper, we introduce an optimal control for a SIR model governed by an ODE system with time delay. We extend the stability studies of model (2.2) in section 2, by incorporating suitable controls. We consider two control strategies in the optimal control model, namely: the vaccination and treatment strategies. The model has a time delays that represent the incubation period. We derive the first-order necessary conditions for the optimal control and perform numerical simulations to show the effectiveness as well as the applicability of the model for different values of the time delays. These numerical simulations show that the model is sensitive to the delays representing the incubation period.
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Optimal treatment of an SIR epidemic model with time delay
Gul Zaman, Yong Han Kang, Il Hyo Jung · Biosystems · 2009 · 150 citations