Prenatal caffeine exposure increases the susceptibility to non-alcoholic fatty liver disease in female offspring rats via activation of GR-C/EBPα-SIRT1 pathway

Design and validation of a histological scoring system for nonalcoholic fatty liver disease†

David E. Kleiner, Elizabeth M. Brunt, Mark L. Van Natta et al. · Hepatology · 2005 · 10.7K citations

Medicine, Pathology, Gastroenterology +16

Dose translation from animal to human studies revisited

Shannon Reagan‐Shaw, Minakshi Nihal, Nihal Ahmad · The FASEB Journal · 2007 · 6.3K citations

Medicine, Pharmacology, Translational Sciences +13

Prevalence of Fatty Liver in Children and Adolescents

Jeffrey B. Schwimmer, Reena Deutsch, Tanaz Kahen et al. · PEDIATRICS · 2006 · 1.5K citations

Medicine, Pathology, Pediatrics +15

Defective Lipolysis and Altered Energy Metabolism in Mice Lacking Adipose Triglyceride Lipase

Guenter Haemmerle, Achim Lass, Robert Zimmermann et al. · Science · 2006 · 1.4K citations · Full text

Life Sciences, Biochemistry, Physiology +17

SIRT1 Deacetylates and Inhibits SREBP-1C Activity in Regulation of Hepatic Lipid Metabolism*

Bhaskar Ponugoti, Dong-Hyun Kim, Zhen Xiao et al. · Journal of Biological Chemistry · 2010 · 544 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15