Autophagy · 2019 · 65 citations · 77 references
Life SciencesCell BiologyNeuroscienceAutophagyMolecular NeuroscienceNeurodegenerationLate EndosomesLysosomal DegradationLysosomal DysfunctionLysosome BiologyNeurodegenerative DiseasesNeurodegenerative DisordersAmyotrophic Lateral Sclerosis AutophagyAmyotrophic Lateral Sclerosis Lysosomal DysfunctionAmyotrophic Lateral Sclerosis PathologyAutophagy PathwayEr Stress In NeurodegenerationLysosomal Degradation PathwaysLysosomal Storage DefectsLysosome Dysfunction
Vap33, and human VAPA and VAPB).
77
A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
Alan E. Renton, Elisa Majounie, Adrian J. Waite et al. · Neuron · 2011 · 4.5K citations · Full text
Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation
Mark E. Gurney, Haifeng Pu, Arlene Y. Chiu et al. · Science · 1994 · 4.1K citations
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
Taichi Hara, Kenji Nakamura, Makoto Matsui et al. · Nature · 2006 · 3.8K citations
Loss of autophagy in the central nervous system causes neurodegeneration in mice
Masaaki Komatsu, Satoshi Waguri, Tomoki Chiba et al. · Nature · 2006 · 3.5K citations
TFEB Links Autophagy to Lysosomal Biogenesis
Carmine Settembre, Chiara Di Malta, Vinicia Assunta Polito et al. · Science · 2011 · 3.3K citations