Concepedia

<i>LncIRS1</i> controls muscle atrophy via sponging miR‐15 family to activate IGF1‐PI3K/AKT pathway

Zhenhui Li, Bolin Cai, Bahareldin Ali Abdalla, Xuenong Zhu, Ming Zheng, Peigong Han, Qinghua Nie, Xiquan Zhang

Journal of Cachexia Sarcopenia and Muscle · 2019 · 192 citations · 33 references

DOIFull text

Open access

Abstract

The newly identified lncIRS1 acts as a sponge for miR-15 family to regulate IRS1 expression, resulting in promoting skeletal muscle myogenesis and controlling atrophy.

References

33

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