Long-Term Outcome of WHIM Syndrome in 18 Patients: High Risk of Lung Disease and HPV-Related Malignancies

Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease

Paolo A. Hernandez, Robert J. Gorlin, John N. Lukens et al. · Nature Genetics · 2003 · 705 citations

Life Sciences, Immunology, Molecular Genetics +11

WHIM syndromes with different genetic anomalies are accounted for by impaired CXCR4 desensitization to CXCL12

Karl Balabanian · Blood · 2004 · 313 citations

Life Sciences, Genetics, Molecular Genetics +5

WHIM syndrome, an autosomal dominant disorder: Clinical, hematological, and molecular studies

Robert J. Gorlin, Bruce D. Gelb, George A. Díaz et al. · American Journal of Medical Genetics · 2000 · 203 citations

Medicine, Immunology, Pathology +14

Myelokathexis — A New Form of Chronic Granulocytopenia

Wolf W. Zuelzer, Ruth K. Evans, Jody Goodman · New England Journal of Medicine · 1964 · 189 citations

Medicine, Hematology, Immunology +9

Altered leukocyte response to CXCL12 in patients with warts hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome

Anna Virginia Gulino, Daniele Moratto, Silvano Sozzani et al. · Blood · 2004 · 184 citations · Full text

Life Sciences, Hematology, Immunology +10