International Journal of Environmental Research and Public Health · 2019 · 30 citations · 24 references
MedicineGeriatric MedicineHealth SciencesGeriatric AssessmentGeriatric CareGeriatricsChronic DiseaseComorbid Medical ConditionsComorbidityDiabetes MellitusQuality Of LifeQuality Of Life AssessmentBurden Of Illness MeasurementChronic Disease ComorbidityComorbid Chronic DiseaseComorbid Diabetes MellitusComorbid Medical IllnessComorbidity AnalysisElderly PopulationTobit Regression
Type 2 diabetes mellitus (T2DM) is a major cause of disease burden in the elderly population. This study aimed to measure the quality of life (QOL) among patients with T2DM and the associations between co-morbidities and QOL. A cross-sectional study was conducted on 194 patients with T2DM. The minimal clinically important difference (MCID) scores were used to indicate the clinically meaningful differences of comorbidities on quality of life. A Tobit regression was employed to find relationships between QOL and comorbidities. The mean scores of QOL domains were 50.8 (SD = 13.2) in physical, 62.4 (SD = 11.5) in psychological, 52.3 (SD = 10.2) in social relationship, and 64.3 (SD = 10.1) in environmental. Digestive and neuropsychiatric diseases had the strongest negative associations with physical QOL of patients. Neuropsychiatric diseases also had the biggest effect on psychological and environmental QOL. Meanwhile, in the social domain, respiratory diseases had the greatest effect. In conclusion, patients with T2DM struggled to perform physical functions. In addition, comorbidities significantly reduced the QOL of T2DM patients.
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Roman Jaeschke, Joel Singer, Gordon Guyatt · Controlled Clinical Trials · 1989 · 4.9K citations
Diabetes, Depression, and Quality of Life
Robert D. Goldney, Pat Phillips, Laura J. Fisher et al. · Diabetes Care · 2004 · 619 citations · Full text