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Novel 2,4-disubstituted quinazolines as cytotoxic agents and JAK2 inhibitors: Synthesis, in vitro evaluation and molecular dynamics studies

Medicinal ChemistryJak2 InhibitorsDrug DiscoveryMedicineRational Drug DesignMechanism Of ActionNovel 2,4-Disubstituted QuinazolinesPharmacotherapyAnti-cancer AgentDrug DevelopmentPharmacologyPharmaceutical ChemistryBiomolecular EngineeringMolecular Dynamics Studies