Lipopolysaccharide mediates time-dependent macrophage M1/M2 polarization through the Tim-3/Galectin-9 signalling pathway

Assessment of Clinical Criteria for Sepsis

Christopher W. Seymour, Theodore J. Iwashyna, Frank M. Brunkhorst et al. · JAMA · 2016 · 3.8K citations · Full text

Veterinary Medicine, Infectious Diseases, Internal Medicine +17

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

Laurent Monney, Catherine A. Sabatos, Jason L. Gaglia et al. · Nature · 2002 · 1.6K citations

Life Sciences, Cell Biology, Immunology +16

The Isolation and Characterization of Murine Macrophages

Xia Zhang, Ricardo Gonçalves, David M. Mosser · Current Protocols in Immunology · 2008 · 1.6K citations · Full text

Life Sciences, Immunology, Physiology +8

TLR4, but not TLR2, mediates IFN-β–induced STAT1α/β-dependent gene expression in macrophages

Vladimir Y. Toshchakov, Bryan W. Jones, Pin‐Yu Perera et al. · Nature Immunology · 2002 · 809 citations

Life Sciences, Immunology, Molecular Biology +14

The Phosphatidylinositol 3-Kinase-Akt Pathway Limits Lipopolysaccharide Activation of Signaling Pathways and Expression of Inflammatory Mediators in Human Monocytic Cells

Mausumee Guha, Nigel Mackman · Journal of Biological Chemistry · 2002 · 789 citations · Full text

Life Sciences, Cell Biology, Immunology +17