Mucosal IL13RA2 expression predicts nonresponse to anti‐TNF therapy in Crohn's disease

Abstract

Increased mucosal IL13RA2 expression is associated with an increased mucosal TNF burden in CD patients. In view of its specificity for prediction of anti-TNF therapy resistance, mucosal IL13RA2 expression is a potential biomarker for therapy selection and/or for the need of increased anti-TNF drug dosing.