Synthesis and function of amphiphilic glucan dendrimers as nanocarriers for protein delivery

Abstract

We report the combined enzymatic synthesis of five glucan dendrimers with control of molecular weight and particle size. Amphiphilic properties were introduced through dodecyl group substitution. A Tokyo-green fluorescence assay showed that amphiphilic glucan dendrimers were able to successfully deliver active β-galactosidase to cells.