Delayed daily activity and reduced NREM slow-wave power in the APPswe/PS1dE9 mouse model of Alzheimer's disease

Sleep Drives Metabolite Clearance from the Adult Brain

Lulu Xie, Hongyi Kang, Qiwu Xu et al. · Science · 2013 · 5.3K citations · Full text

Life Sciences, Neurobiology, Neuroscience +15

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues

Seung Hee Yoo, Shin Yamazaki, Phillip L. Lowrey et al. · Proceedings of the National Academy of Sciences · 2004 · 2.4K citations · Full text

Nursing, Neuroscience, Physiology +17

A functional analysis of circadian pacemakers in nocturnal rodents

Colin S. Pittendrigh, Serge Daan · Journal of Comparative Physiology A · 1976 · 2.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

Joanna L. Jankowsky, Daniel J. Fadale, Jeffrey C. Anderson et al. · Human Molecular Genetics · 2003 · 1.6K citations · Full text

Life Sciences, Neurology, Neuroscience +16

Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves, and sleep spindle activity in humans

Journal of Neuroscience · 1995 · 1.4K citations · Full text

Life Sciences, Neuroscience, Physiology +10