Enantioselective Synthesis and Epimerization Behavior of a Chiral S‐Shaped [11]Helicene‐Like Molecule Having Collision between Terminal Benzene Rings

Abstract

It has been established that a chiral S‐shaped [11]helicene‐like molecule can be synthesized with high ee value along with a meso form by the rhodium(I)/( R )‐difluorphos complex‐mediated enantioselective intramolecular double [2+2+2] cycloaddition of a 2‐naphthol‐linked hexayne, even though this chiral helicene has the collision between the terminal benzene rings. Epimerization behavior of the chiral and meso [11]helicene‐like molecules have also been disclosed.